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BCL2A1 Rabbit anti-Human, Clone: 3E4, Bioss
SDP

Catalog No. 501989528
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50-198-9528 100 μL
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Catalog No. 50-198-9528 Supplier Bioss Supplier No. BSM52023R
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Description

Rabbit Monoclonal Antibody

Bcl-2 related Protein A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.

Specifications

Antigen BCL2A1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 3E4
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene BCL2A1
Gene Accession No. Q16548
Gene Alias A1; A1-A; ACC1; ACC-1; ACC2; ACC-2; B cell leukemia/lymphoma 2 related protein A1a; BB218357; B-cell leukemia/lymphoma 2 related protein A1; B-cell leukemia/lymphoma 2 related protein A1a; B-cell leukemia/lymphoma 2 related protein A1d; BCL2 related protein A1; BCL2A1; Bcl2a1a; Bcl2a1d; BCL2L5; Bcl2-L-5; Bcl-2-like protein 5; Bcl-2-related protein A1; BCL2-related protein A1; BCL2-related protein A1d; BFL1; Bfl-1; GRS; GRS protein; HBPA1; hematopoietic BCL2-related protein A1; Hemopoietic-specific early response protein; Protein BFL-1; Protein GRS
Gene Symbols BCL2A1
Host Species Rabbit
Immunogen Recombinant human BCL2A1 protein, full length.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 597
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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