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BCL2L1 Mouse anti-Human, Clone: SPM337, Abnova™

Catalog No. 89933631 Shop All Abnova Corporation Products
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89-933-631 100 μg
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Catalog No. 89-933-631 Supplier Abnova Corporation Supplier No. MAB13151
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Description

Mouse monoclonal antibody raised against synthetic peptide of human BCL2L1.

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq]

Sequence: Cys-QSNRELVVDFLS

Specifications

Antigen BCL2L1
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Classification Monoclonal
Clone SPM337
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against synthetic peptide of human BCL2L1.
Dilution Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be dete
Formulation In 10mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Alias BCL-XL/S/BCL2L/BCLX/Bcl-X/DKFZp781P2092/bcl-xL/bcl-xS
Gene Symbols BCL2L1
Host Species Mouse
Immunogen A synthetic peptide corresponding to amino acids 3-14 of human BCL2L1.
Purification Method Protein A/G purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 598
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Isotype IgG2a
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