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Invitrogen™ BCL2L10 Polyclonal Antibody
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Catalog No. PIPA5100704
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PIPA5100704 100 μL
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Catalog No. PIPA5100704 Supplier Invitrogen™ Supplier No. PA5100704
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total BCL2L10.

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BCL2L10
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene BCL2L10
Gene Accession No. Q9HD36, Q9Z0F3
Gene Alias AA420380; anti-apoptotic protein Boo; Anti-apoptotic protein NrH; apoptosis regulator Bcl-B; AU023065; Bcl-2 homolog Diva; BCL2 like 10; BCL2L10; bcl2-L-10; Bcl2-like 10; BCL2-like 10 (apoptosis facilitator); bcl-2-like protein 10; BCLB; BCL-B; Boo; C85687; death inducer binding to vBcl-2 and Apaf-1; Diva
Gene Symbols BCL2L10
Host Species Rabbit
Immunogen A synthesized peptide derived from human BCL2L10(Accession Q9HD36), corresponding to amino acid residues G122-Q172.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10017, 12049
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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