Invitrogen™ BCL2L12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522209

Catalog No. PIPA522209

Description

Recommended positive controls: Molt-4. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: BCL2L12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BCL2L12
• Gene Alias: 2810475P17Rik; 5430429M05Rik; BCL2 like 12; Bcl-2 related proline-rich protein; Bcl2l12; Bcl2-L12; Bcl2-L-12; BCL2-like 12 (proline rich); bcl-2-like protein 12; Bcl-2-related proline-rich protein; Bcl-L12; BPR
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 83596
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.37 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9HB09
• Gene Symbols: BCL2L12
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human BCL2L12. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG