Invitrogen™ BCL6 Recombinant Rabbit Monoclonal Antibody (BLR143H)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA544473

Catalog No. PIMA544473

Description

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin's lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt's lymphomas and in nodular, lymphocyte predominant Hodgkin's disease.

Specifications

• Antigen: BCL6
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: BBS with 0.09% sodium azide; pH 7.8-8.6
• Gene Accession No.: P41182
• Gene Symbols: BCL6
• Immunogen: Peptide representing a region between residue 375 and 425 of Human B-cell lymphoma 6 protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: BLR143H
• Conjugate: Unconjugated
• Gene: BCL6
• Gene Alias: B cell CLL/lymphoma 6; B cell leukemia/lymphoma 6; B-cell CLL/lymphoma 6; B-cell CLL/lymphoma 6 (zinc finger protein 51); B-cell leukemia/lymphoma 5; B-cell leukemia/lymphoma 6; B-cell lymphoma 5 protein; B-cell lymphoma 5 protein (BCL5); B-cell lymphoma 6 protein; B-cell lymphoma 6 protein homolog; B-cell lymphoma 6 protein transcript; BCL5; BCL-5; Bcl6; Bcl-6; BCL6 transcription repressor; BCL6A; cys his2 zinc finger transcription factor; cys-his2 zinc finger transcription factor; LAZ3; LAZ-3 protein; Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3); lymphoma-associated zinc finger gene on chromosome 3; protein LAZ-3; ZBTB27; zinc finger and BTB domain-containing protein 27; Zinc finger and BTB domain-containing protein 27 (ZBTB27); Zinc finger protein 51; Zinc Finger Protein 51 (ZNF51); zinc finger transcription factor BCL6S; ZNF51
• Host Species: Rabbit
• Purification Method: purified
• Regulatory Status: RUO
• Gene ID (Entrez): 604
• Content And Storage: 4°C
• Form: Liquid