Invitrogen™ BCL7A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527123

Catalog No. PIPA527123

Description

Recommended positive controls: HeLaS3, Neuro2A, GL261. Predicted reactivity: Mouse (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: BCL7A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BCL7A
• Gene Alias: 4432415N06Rik; AI448316; B cell CLL/lymphoma 7A; B-cell CLL/lymphoma 7 protein family member A; B-cell CLL/lymphoma 7A; B-cell CLL/lymphoma-7; BCL 7; BCL tumor suppressor 7A; BCL7; Bcl7a; LOC690085; similar to B-cell CLL/lymphoma 7A
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 605, 690085, 77045
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q4VC05, Q9CXE2
• Gene Symbols: BCL7A
• Immunogen: Synthetic peptide corresponding to a region within amino acids 148 and 210 of Human BCL7A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov