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Invitrogen™ BCL7A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527123

Catalog No. PIPA527123


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Description

Description

Recommended positive controls: HeLaS3, Neuro2A, GL261. Predicted reactivity: Mouse (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

BCL7A
Polyclonal
Unconjugated
BCL7A
4432415N06Rik; AI448316; B cell CLL/lymphoma 7A; B-cell CLL/lymphoma 7 protein family member A; B-cell CLL/lymphoma 7A; B-cell CLL/lymphoma-7; BCL 7; BCL tumor suppressor 7A; BCL7; Bcl7a; LOC690085; similar to B-cell CLL/lymphoma 7A
Rabbit
Antigen affinity chromatography
RUO
605, 690085, 77045
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Q4VC05, Q9CXE2
BCL7A
Synthetic peptide corresponding to a region within amino acids 148 and 210 of Human BCL7A.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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