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Invitrogen™ BCLAF1 Polyclonal Antibody
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Catalog No. PIPA524468
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400 μL
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Catalog No. Quantity
PIPA524468 400 μL
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Catalog No. PIPA524468 Supplier Invitrogen™ Supplier No. PA524468
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Description

Rabbit Polyclonal Antibody

BCLAF1 Polyclonal Antibody for Western Blot, IHC (P)

BCLAF1 is an intracellular, death promoting transcriptional repressor of survival genes that interacts with several members of the BCL2 family of proteins. It shows homology to the basic leucine zipper (bzip) and MYB DNA binding domains.From recent research it can be concluded that in case of apoptotic cells this protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope. When over expressed this protein induces apoptosis and can be suppressed by co-expression of BCL2 proteins. Also known as BTF, it triggers a proapoptotic signal, potentially helpful to overcome the resistance to STI571.BCLAF1 is found to express mostly in skeletal muscles.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BCLAF1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene BCLAF1
Gene Accession No. Q9NYF8
Gene Alias 2610102K23Rik; 2700025J07Rik; 2810454G14Rik; 5730534O06Rik; Aa2-041; AI450190; AW556225; BCL2 associated transcription factor 1; bcl-2-associated transcription factor 1; BCL2-associated transcription factor 1; Bcl-2-associated transcription factor 1-like protein; BCLAF1; BCLAF1 and THRAP3 family member 1; bK211L9.1; BP-1; BTF; Btf-s; KIAA0164; mKIAA0164
Gene Symbols BCLAF1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 658-687 amino acids from the C-terminal region of human BCLAF1.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9774
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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