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BCLAF1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987847
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100 μL
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50-198-7847 100 μL
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Catalog No. 50-198-7847 Supplier Bioss Supplier No. BS7583R
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Description

Rabbit Polyclonal Antibody

BCLAF1 is an intracellular, death promoting transcriptional repressor of survival genes that interacts with several members of the BCL2 family of proteins. It shows homology to the basic leucine zipper (bzip) and MYB DNA binding domains.From recent research it can be concluded that in case of apoptotic cells this protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope. When over expressed this protein induces apoptosis and can be suppressed by co-expression of BCL2 proteins. Also known as BTF, it triggers a proapoptotic signal, potentially helpful to overcome the resistance to STI571.BCLAF1 is found to express mostly in skeletal muscles.

Specifications

Antigen BCLAF1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene BCLAF1
Gene Accession No. Q9NYF8
Gene Alias 2610102K23Rik; 2700025J07Rik; 2810454G14Rik; 5730534O06Rik; Aa2-041; AI450190; AW556225; BCL2 associated transcription factor 1; Bcl-2-associated transcription factor 1; BCL2-associated transcription factor 1; Bclaf1; BCLAF1 and THRAP3 family member 1; bK211L9.1; BOS_9848; BP-1; Btf; Btf-s; KIAA0164; mKIAA0164
Gene Symbols BCLAF1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human BCLAF1 .
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9774
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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