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Invitrogen™ BCOR Polyclonal Antibody
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Catalog No. PIPA5106545
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100 μL
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PIPA5106545 100 μL
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Catalog No. PIPA5106545 Supplier Invitrogen™ Supplier No. PA5106545
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total BCOR.

Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).
TRUSTED_SUSTAINABILITY

Specifications

Antigen BCOR
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Bcor
Gene Accession No. Q6W2J9, Q8CGN4
Gene Alias 5830466J11Rik; 8430401K06Rik; ANOP2; BCL6 corepressor; BCL-6 corepressor; BCL6 co-repressor; BCL6 interacting corepressor; BCL-6 interacting corepressor; Bcor; BcorR; D930024N20Rik; Kiaa1575; MAA2; MCOPS2; mKIAA1575; RGD1562735
Gene Symbols Bcor
Host Species Rabbit
Immunogen A synthesized peptide derived from human BCOR(Accession Q6W2J9), corresponding to amino acid residues V1237-F1287.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54880, 71458
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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