Invitrogen™ BCOR Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142066

Catalog No. PIPA5142066

Description

Additional Information: This antibody is expected to recognise all reported isoforms (NP_060215.4; NP_001116855.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).

Specifications

• Antigen: BCOR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Bcor
• Gene Alias: 5830466J11Rik; 8430401K06Rik; ANOP2; BCL6 corepressor; BCL-6 corepressor; BCL6 co-repressor; BCL6 interacting corepressor; BCL-6 interacting corepressor; Bcor; BcorR; D930024N20Rik; Kiaa1575; MAA2; MCOPS2; mKIAA1575; RGD1562735
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 54880
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q6W2J9
• Gene Symbols: Bcor
• Immunogen: Peptide with sequence LSATPLYGNVHSW-C (aa 2-14).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG