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Invitrogen™ BCS1L Polyclonal Antibody
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Catalog No. PIPA596745
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100 μL
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PIPA596745 100 μL
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Catalog No. PIPA596745 Supplier Invitrogen™ Supplier No. PA596745
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RKGVQLGLVA FRRHYMITLE VPARDRSYAW LLSWLTRHST RTQHLSVETS YLQHESGRIS TKFEFVPSPG NHFIWYRGKW IRVERSREMQ MIDLQTGTPW ESVTFTALGT DRKVFFNILE EARELALQQE EGKTVMYTAV GSEWRPFGYP RRRRPLNSVV LQQGLADRIV RDVQEFIDNP KWYTDRGIPY RRGYLLYGPP GCGKSSFI; Positive Samples: HepG2, SKOV3, MCF7, HeLa, Mouse heart, Mouse liver; Cellular Location: Mitochondrion inner membrane, Single-pass membrane protein.

This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Five alternatively spliced transcripts encoding the same protein have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BCS1L
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.08 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Bcs1l
Gene Accession No. Q9CZP5, Q9Y276
Gene Alias 9130022O19Rik; BC1 (ubiquinol-cytochrome c reductase) synthesis-like; BCS; BCS1; BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Bcs1l; BCS1-like (yeast); BCS1-like protein; BJS; FLNMS; GRACILE; h-BCS; h-BCS1; Hs.6719; MC3DN1; mitochondrial chaperone BCS1; mitochondrial complex III assembly; PTD
Gene Symbols Bcs1l
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 33-240 of human BCS1L (NP_0043191).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 301514, 617, 66821
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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