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BDCA-2 (CD303) Mouse, anti-Human, R718, Clone: V24-785, BD OptiBuild™

Catalog No. BDB751950 Shop All BD Biosciences Products
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BDB751950 50 μg
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Catalog No. BDB751950 Supplier BD Biosciences Supplier No. 751950
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Description

Mouse Monoclonal Antibody

The V24-785 monoclonal antibody binds specifically to BDCA-2 (Blood Dendritic Cell Antigen 2), also known as CD303. As a member of the C-type lectin (CLEC) superfamily, it is an adhesion receptor that binds to galactose-terminated desialylated glycans on cell surfaces and on serum IgG. In the blood, BDCA-2 is expressed only on plasmacytoid dendritic cells (pDC). TLR-9 mediates the production of large amounts of IFN-α and IFN-β by activated pDC, and crosslinking of BDCA-2 inhibits that response.

TRUSTED_SUSTAINABILITY

Specifications

Antigen BDCA-2 (CD303)
Applications Flow Cytometry
Classification Monoclonal
Clone V24-785
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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