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Tocris Bioscience™ BDY FL Thalidomide
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Catalog No. 76332
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76-332 2 mg
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Catalog No. 76-332 Supplier Tocris Bioscience™ Supplier No. 7633/2
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Description

High affinity fluorescent probe for TR-FRET cereblon binding assay

BDY FL Thalidomide is a high-affinity fluorescent probe (Kd = 3.6 nM). It can be used in time-resolved fluorescence resonance energy-transfer (TR-FRET) cereblon binding assays for PROTAC™ Degrader development. This assay is highly sensitive, selective, and stable. Excitation and emission maxima (λ) are 502 and 510 nm, respectively.

PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.

Specifications

Chemical Name or Material 3-(5,5-Difluoro-7,9-dimethyl-5 H-5λ4,6λ4-dipyrrolo[1,2-c:2 ',1 '-f][1,3,2 ]diazaborinin-3-yl)-N-(8-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)octyl)propenamide
CAS 2740620-18-0
Quantity 2 mg
Target Fluorescent Probes
Molecular Formula C37H43BF2N6O7
Purity 0.95
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