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Beclin 1 Mouse anti-Human, Clone: 7B12, Bioss
SDP

Catalog No. 501979948
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100 μL
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50-197-9948 100 μL
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Catalog No. 50-197-9948 Supplier Bioss Supplier No. BSM33323M
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Description

Mouse Monoclonal Antibody

Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.

Specifications

Antigen Beclin 1
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 7B12
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene BECN1
Gene Accession No. Q14457
Gene Alias 4921513J16Rik; 5430417M23Rik; APG6; Atg6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2 interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; beclin1; Beclin-1; Beclin-1-C 35 kDa; Beclin-1-C 37 kDa; BECN1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; GT197; hypothetical protein MGC73097; myosin-like BCL2 interacting protein; Protein GT197; testis secretory sperm-binding protein Li 215e; VPS30; zgc:73097
Gene Symbols BECN1
Host Species Mouse
Immunogen KLH conjugated synthetic peptide derived from human Beclin 1.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8678
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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