Invitrogen™ Beclin 2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA146312

Catalog No. PIPA146312

Description

Suggested positive control: 293 whole cell lysate, HEK293 kidney cell lysates and MCC827 lung cell lysates. Does not appear to work with A431 lysates.

Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1. [UniProt].

Specifications

• Antigen: Beclin 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Becn2
• Gene Alias: Bcl-2; BCS2; beclin 1, autophagy related, pseudogene 1; beclin 2; beclin-1 autophagy-related pseudogene 1; Beclin-1-like protein 1; Beclin-2; BECN1L1; BECN1P1; BECN2; Gm104; PFM 2; PFM2; PRDM 5; PRDM5; PRDM5 protein; RGD1563293; similar to Beclin 1 (Coiled-coil myosin-like BCL2-interacting protein)
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 226720, 441925
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.13 mg/mL
• Formulation: PBS with 30% glycerol and 0.1% sodium azide
• Gene Accession No.: A8MW95, P0DM65
• Gene Symbols: Becn2
• Immunogen: Synthetic peptide corresponding to internal residues 200-300 of the human beclin 2. [NCBI# XP_945075].
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG