BECN1 Monoclonal Antibody (OTI2C5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA502615

Catalog No. 50-167-3655

Description

Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.

Specifications

• Antigen: BECN1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q14457
• Gene Symbols: BECN1
• Immunogen: Full length human recombit protein of human BECN1 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI2C5
• Conjugate: Unconjugated
• Gene: BECN1
• Gene Alias: ATG6, VPS30, beclin1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8678
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid