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Invitrogen™ BEND3 Polyclonal Antibody
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Catalog No. PIPA553659
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100 μL
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PIPA553659 100 μL
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Catalog No. PIPA553659 Supplier Invitrogen™ Supplier No. PA553659
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CLPQLNDFFS RFWAQREMED SQPSGQVASF FEAEQVDPGH FLDNKDQEEA LSLDRSSTIA SDHVVDTQDL TEFLDEASSP GEFAVFLLHR LFPELFDHRK LGEQYSCYGD GGKQELDPQR LQIIRNYTEI YFPD Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination (PubMed:21914818, PubMed:26100909). Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites. Stimulates the ERCC6L translocase and ATPase activities (PubMed:28977671). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen BEND3
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene BEND3
Gene Accession No. Q5T5X7
Gene Alias BEN domain containing 3; BEN domain-containing protein 3; Bend3; KIAA1553; mKIAA1553
Gene Symbols BEND3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human BEND3. Recombinant protein control fragment (Product #RP-90911).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57673
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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