Invitrogen™ BERP Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518136

Catalog No. PIPA518136

Description

This antibody is predicted to react with bovine, canine, human and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

The protein encoded by this gene is a member of the tripartite motif family, also called the 'RING-B-box-coiled-coil' subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified.

Specifications

• Antigen: BERP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRIM3
• Gene Alias: Berp; BERP1; brain expressed ring finger; brain-expressed RING finger protein; Hac1; RING finger protein 22; RING finger protein 97; RING finger protein HAC1; RNF22; RNF97; Trim3; tripartite motif containing 3; tripartite motif protein 3; tripartite motif protein TRIM3; tripartite motif-containing 3; tripartite motif-containing protein 3
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 10612, 55992, 83616
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O70277, O75382, Q9R1R2
• Gene Symbols: TRIM3
• Immunogen: Synthetic peptide sequence (AKREDSPGPEVQP) corresponding to the N-terminus amino acids of TRIM3 (aa 2-14).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG