Invitrogen™ BERP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101070

Catalog No. PIPA5101070

Description

Antibody detects endogenous levels of total TRIM3.

The protein encoded by this gene is a member of the tripartite motif family, also called the 'RING-B-box-coiled-coil' subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified.

Specifications

• Antigen: BERP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRIM3
• Gene Alias: Berp; BERP1; brain expressed ring finger; brain-expressed RING finger protein; Hac1; RING finger protein 22; RING finger protein 97; RING finger protein HAC1; RNF22; RNF97; Trim3; tripartite motif containing 3; tripartite motif protein 3; tripartite motif protein TRIM3; tripartite motif-containing 3; tripartite motif-containing protein 3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10612, 55992, 83616
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O70277, O75382, Q9R1R2
• Gene Symbols: TRIM3
• Immunogen: A synthesized peptide derived from human TRIM3(Accession O75382), corresponding to amino acid residues V435-E485.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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