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Invitrogen™ Bestrophin 2 Polyclonal Antibody
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Catalog No. PIPA5111228
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100 μL
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Catalog No. Quantity
PIPA5111228 100 μL
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Catalog No. PIPA5111228 Supplier Invitrogen™ Supplier No. PA5111228
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RRLSFLLRKN SCVSEASTGA SCSCAVVPEG AAPECSCGDP LLDPGLPEPE APPPAGPEPL TLIPGPVEPF SIVTMP Highest antigen sequence indentity to the following orthologs: Rat - 68%, Mouse - 65%.

Best2 forms calcium-sensitive chloride channels and is permeable to bicarbonate. The Best2 gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in the Best2 gene is associated with vitelliform macular dystrophy. The Best2 gene is mainly expressed in the retinal pigment epithelium and colon. Diseases associated with BEST2 include Vitelliform Macular Dystrophy and Bestrophinopathy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Bestrophin 2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene BEST2
Gene Accession No. Q8NFU1
Gene Alias BEST2; bestrophin 2; bestrophin-2; Hbest2; vitelliform macular dystrophy 2-like 1; vitelliform macular dystrophy 2-like protein 1; VMD2L1; VMD2L-1; VMD2-like gene 1
Gene Symbols BEST2
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human Bestrophin 2. Recombinant protein control fragment (Product #RP-98318).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54831
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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