Invitrogen™ Bestrophin 3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA533365

Catalog No. PIPA533365

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Marmoset, Bat (95%) Hamster, Elephant, Panda, Bovine, Pig (90%) Dog, Rabbit (85%).

BEST3 belongs to the bestrophin family of anion channels, which includes BEST1, the gene mutant in vitelliform macular dystrophy (VMD), and 2 other BEST1-like genes, BEST2 and BEST4. Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length.

Specifications

• Antigen: Bestrophin 3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BEST3
• Gene Alias: BEST3; bestrophin 3; bestrophin-3; mBest4; vitelliform macular dystrophy 2-like 3; vitelliform macular dystrophy 2-like protein 3; Vmd2l3
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 144453
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q8N1M1
• Gene Symbols: BEST3
• Immunogen: Synthetic 20 amino acid peptide from internal region of human BEST3.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG