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Invitrogen™ Bestrophin 3 Polyclonal Antibody
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Catalog No. PIPA562985
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PIPA562985 100 μL
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Catalog No. PIPA562985 Supplier Invitrogen™ Supplier No. PA562985
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Rabbit Polyclonal Antibody

Immunogen sequence: VDEMHMSLPK MKKDIYWDDS AARPPYTLAA ADYCIPSFLG STVQMGLSGS DFPDEEWLWD YEKHGHRHSM IRRVKRFLSA HEHPSSPRRR SYRRQTSDSS MFLPRDDLSP ARDLLDVPSR NPPRASPTWK KSCFPEGSPT L Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 81%.

BEST3 belongs to the bestrophin family of anion channels, which includes BEST1, the gene mutant in vitelliform macular dystrophy (VMD), and 2 other BEST1-like genes, BEST2 and BEST4. Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Bestrophin 3
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene BEST3
Gene Accession No. Q8N1M1
Gene Alias BEST3; bestrophin 3; bestrophin-3; mBest4; vitelliform macular dystrophy 2-like 3; vitelliform macular dystrophy 2-like protein 3; Vmd2l3
Gene Symbols BEST3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human VMD2L3. Recombinant protein control fragment (Product #RP-91144).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 144453
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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