Invitrogen™ beta-2 Adrenergic Receptor Monoclonal Antibody (5G3B5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA538441

Catalog No. PIMA538441

Description

This antibody has been tested in indirect ELISA.

Adrenergic receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind the endogenous catecholamines epinephrine and norepinephrine. Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family. Nine receptor subtypes have been identified thus far including three alpha-1 AR subtypes (1A/D, 1B, and 1C), three alpha-2 ARs (2A, 2B, and 2C), and three beta AR subtypes (1, 2, and 3). ARs participate in either the onset or maintenance of several disease states including hypertension, cardiac dysfunction (congestive heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence.

Specifications

• Antigen: beta-2 Adrenergic Receptor
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: P07550, P10608
• Gene Symbols: Adrb2
• Immunogen: Purified recombinant fragment of human ADRB2 (aa: 302-413) expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 5G3B5
• Conjugate: Unconjugated
• Gene: Adrb2
• Gene Alias: Adrb2; Adrb-2; ADRB2R; ADRBR; Adrenergic beta 2- receptor surface; adrenergic receptor beta 2; adrenergic receptor, beta 2; adrenergic, beta-2, receptor, surface; adrenergic, beta-2-, receptor, surface; adrenoceptor beta 2; adrenoceptor beta 2 surface; adrenoceptor beta 2, surface; AR beta2; B2AR; Badm; BAR; beta 2-AR; beta-2 adrenergic receptor; Beta-2 adrenoceptor; beta-2 adrenoreceptor; beta-2-adrenergic receptor; beta2-adrenergic receptor; beta2-Adrenoreceptor; BETA2AR; catecholamine receptor; Gpcr7; HGNC:286
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 154, 24176
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid