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Invitrogen™ beta-2 Defensin Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA545065
Description
Peptide sequence: LLFSFLFIFL MPLPGVFGGI GDPVTCLKSG AICHPVFCPR RYKQIGTCGL Sequence homology: Human: 100%.
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.
Specifications
beta-2 Defensin | |
Polyclonal | |
Unconjugated | |
DEFB4A | |
BD-2; beta defensin 2; beta defensin-2; Beta-defensin 2; Beta-defensin 4A; DEFB102; DEFB2; DEFB-2; DEFB4; DEFB4A; DEFB4B; Defensin beta 2; defensin beta 4A; Defensin beta2; defensin, beta 2; defensin, beta 4; defensin, beta 4A; Defensin-beta2; HBD-2; SAP1; Skin-antimicrobial peptide 1 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
1673 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
0.5 mg/mL | |
PBS with 2% sucrose and 0.09% sodium azide | |
O15263 | |
DEFB4A | |
Synthetic peptide directed towards the N-terminal of human DEFB4A (aa 6-55). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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