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Invitrogen™ beta-2 Defensin Polyclonal Antibody
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Catalog No. PIPA547388
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100 μg
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Catalog No. Quantity
PIPA547388 100 μg
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Catalog No. PIPA547388 Supplier Invitrogen™ Supplier No. PA547388
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Description

Goat Polyclonal Antibody

Reconstitute at 0.2 mg/mL in sterile PBS.

Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.
TRUSTED_SUSTAINABILITY

Specifications

Antigen beta-2 Defensin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene DEFB4A
Gene Accession No. O15263
Gene Alias BD-2; beta defensin 2; beta defensin-2; Beta-defensin 2; Beta-defensin 4A; DEFB102; DEFB2; DEFB-2; DEFB4; DEFB4A; DEFB4B; Defensin beta 2; defensin beta 4A; Defensin beta2; defensin, beta 2; defensin, beta 4; defensin, beta 4A; Defensin-beta2; HBD-2; SAP1; Skin-antimicrobial peptide 1
Gene Symbols DEFB4A
Host Species Goat
Immunogen E. coli-derived recombinant human beta-Defensin 4/2 Gly24-Pro64.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1673
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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