Invitrogen™ beta-3 Adrenergic Receptor Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597131

Catalog No. PIPA597131

Description

Immunogen sequence: MAPWPHENSS LAPWPDLPTL APNTANTSGL PGVPWEAALA GALLALAVLA TVGGNLLVIV AIAWTPRLQT MTNVFVTSLA AADLVMGLLV VPPAATLALT; Positive Samples: HL-60, K-562; Cellular Location: Cell membrane, Multi-pass membrane protein.

beta 3 Adrenergic Receptor is located mainly in adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Beta adrenergic receptors are involved in the epinephrine and norepinephrine-induced activation of adenylate cyclase through the action of G proteins. beta 3 Adrenergic Receptor expression has been documented in adipose tissues, heart, and in smooth muscle of digestive and urinary tract organs (bladder, colon, small intestine, stomach, ureter). Utilization of alternate promoters and/or 3-prime untranslated regions may result in tissue-specific regulation of the expression of this protein.

Specifications

• Antigen: beta-3 Adrenergic Receptor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADRB3
• Gene Alias: ADRB; ADRB3; Adrb-3; Adrb3r; adrenergic receptor, beta 3; adrenergic, beta-3-, receptor; adrenoceptor beta 3; B3AR; B3bar; beta 3 adrenoceptor; beta 3-AR; beta-3 adrenergic receptor; Beta-3 adrenoceptor; beta-3 adrenoreceptor; Beta-3 AR; beta3-adrenergic receptor; beta3-Adrenoreceptor; BETA3AR; Beta3-AR; FLJ99960
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11556, 155, 25645
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 2.18 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P13945, P25962, P26255
• Gene Symbols: ADRB3
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ADRB3 (NP_0000161).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG