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  6. Invitrogen™ beta-3 Tubulin Monoclonal Antibody (2G10)

Invitrogen™ beta-3 Tubulin Monoclonal Antibody (2G10)

Catalog No. PIMA1118X
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100 μg
20 μL
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Catalog No. Quantity
PIMA1118X 20 μL
PIMA1118 100 μg
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Catalog No. PIMA1118X Supplier Invitrogen™ Supplier No. MA1118X
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Description

Mouse Monoclonal Antibody

MA1-118 was successfully used to detect E18 Sparague Dawley primary cortical neurons. MA1-118 can be used for immunofluorescence analysis of beta III tubulin in the ectoderm derived from human embryonic stem cells. Western blot analysis of MA1-118 detects an ~50 kDa protein in neuronal-type cells. In bovine, a unknown band at ~32 kDa is also detected. MA1-118 shows specificity to beta-3 Tubulin and is non-reactive to lysates from non-neuronal cell types (e.g. HeLa cell lysate).

The betaIII-tubulin isoform is present dominantly in cells of neuronal origin and it is one of the earliest markers of neuronal differentiation. It is regarded as a specific probe for the cells of neuronal origin as well as for the tumours originating from these cells. The betaIII-tubulin is most abundant in cells of neuronal origin, but was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen beta-3 Tubulin
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Multiplex Immunohistochemistry
Classification Monoclonal
Clone 2G10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
Gene TUBB3
Gene Accession No. Q13509, Q2T9S0, Q4QRB4, Q9ERD7
Gene Alias 3200002H15Rik; beta 3 tubulin; beta tubulin 3; beta-4; betaIII-tubulin; CDCBM; CDCBM1; CFEOM3; CFEOM3A; class III beta-tubulin; FEOM3; I79_000194; LOC100341581; M(beta)3; M(beta)6; mc1R; melanocortin receptor 1; Neuron specific beta III Tubulin; neuron-specific class III beta-tubulin; TUBB; Tubb3; TUBB4; tubulin beta; tubulin beta 3 class III; Tubulin beta-3; tubulin beta-3 chain; Tubulin beta-4; Tubulin beta-4 chain; tubulin beta-III; tubulin, beta 3 class III; tubulin, beta, 3; tubulin, beta, 4; Unknown (protein for MGC:134115)
Gene Symbols LOC100341581, TUBB3
Host Species Mouse
Immunogen A synthetic peptide corresponding to amino acids 436-450 from rat neuronal specific beta-3 tubulin.
Purification Method Protein A
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100341581, 100732882, 100760055, 10381, 106509340, 22152, 246118, 768070
Target Species Human, Mouse, Rat, Rabbit, Bovine, Hamster, Pig, Guinea Pig
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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Safety and Handling

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