beta B1 Crystallin Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-2360	100 μL

Catalog No. 50-198-2360 Supplier Bioss Supplier No. BS12582R

Description

Rabbit Polyclonal Antibody

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, undergoes extensive cleavage at its N-terminal extension during lens maturation. It is also a member of a gene cluster with beta-A4, beta-B2, and beta-B3.

Specifications

• Antigen: beta B1 Crystallin
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Crybb1
• Gene Accession No.: P53674
• Gene Alias: 3110006K12Rik; BB1CRY; Beta-B1 crystallin; Beta-crystallin B1; Beta-crystallin B1B; CATCN3; CRYB1; CRYB11; CRYBB1; crystallin beta B1; crystallin, beta B1; CTRCT17; eye lens structural protein
• Gene Symbols: Crybb1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human beta B1 Crystallin.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1414
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG