Invitrogen™ beta Galactosidase Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119823

Catalog No. PIPA5119823

Description

Positive Control: MCF-7 cell lysate, mouse pancreas tissue lysate, rat stomach tissue lysate, PANC-1, rat kidney tissue, human liver tissue, mouse testis tissue. Subcellular Location: Lysosome, perinuclear region.

Beta Galactosidase encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme. This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates. Mutations in this gene have been associated with GM1-gangliosidosis and Morquio B syndrome. Diseases associated with GLB1 include Gm1-Gangliosidosis, Type I and Gm1-Gangliosidosis, Type Ii.

Specifications

• Antigen: beta Galactosidase
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GLB1
• Gene Alias: acid beta-galactosidase; AW125515; betagal; Beta-Gal; Beta-galactosidase; bgal; Bge; Bgl; Bgl-e; Bgl-s; Bgl-t; Bgs; Bgt; C130097A14Rik; EBP; Elastin receptor 1; elastin receptor 1, 67kDa; ELNR1; galactosidase beta 1; galactosidase, beta 1; GLB1; Glb-1; lactase; lysosmal hydrolase; lysosomal beta-galactosidase; lysosomal hydrolase; MPS4B; ßgal; ß-gal; ß-galactosidase
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12091, 2720, 316033
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P16278, P23780
• Gene Symbols: GLB1
• Immunogen: Synthetic peptide within human Beta-galactosidase aa 20-60.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG