Invitrogen™ Beta III Tubulin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5143785

Catalog No. PIPA5143785

Description

This antibody was cross-adsorbed to phospho-betaIII-Tubulin (Ser-444) peptide before affinity purification using unphosphorylated betaIII-Tubulin (Ser-444) peptide (without carrier). The antibody detects a 50 kDa* protein corresponding to the molecular mass of unphosphorylated betaIII-Tubulin on SDS-PAGE immunoblots of purified brain tubulin and mouse brain tissue.

The betaIII-tubulin isoform is present dominantly in cells of neuronal origin and it is one of the earliest markers of neuronal differentiation. It is regarded as a specific probe for the cells of neuronal origin as well as for the tumours originating from these cells. The betaIII-tubulin is most abundant in cells of neuronal origin, but was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues.

Specifications

• Antigen: Beta III Tubulin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TUBB3
• Gene Alias: 3200002H15Rik; beta 3 tubulin; beta tubulin 3; beta-4; betaIII-tubulin; CDCBM; CDCBM1; CFEOM3; CFEOM3A; class III beta-tubulin; FEOM3; I79_000194; LOC100341581; M(beta)3; M(beta)6; mc1R; melanocortin receptor 1; Neuron specific beta III Tubulin; neuron-specific class III beta-tubulin; TUBB; Tubb3; TUBB4; tubulin beta; tubulin beta 3 class III; Tubulin beta-3; tubulin beta-3 chain; Tubulin beta-4; Tubulin beta-4 chain; tubulin beta-III; tubulin, beta 3 class III; tubulin, beta, 3; tubulin, beta, 4; Unknown (protein for MGC:134115)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10381, 22152, 246118
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: ∼0.13 mg/mL
• Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
• Gene Accession No.: Q13509, Q4QRB4, Q9ERD7
• Gene Symbols: TUBB3
• Immunogen: Unphosphorylated betaIII-Tubulin synthetic peptide (coupled to KLH) corresponding to amino acid residues around serine 444 of human betaIII-Tubulin. This sequence is not found in bI or betaII-Tubulin isotypes, but is well conserved in betaIII-Tubulins from rat and mouse.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG