Invitrogen™ beta Lactamase Monoclonal Antibody (8A5.A10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA120370

Catalog No. MA120370

Description

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. Sequence: MSIQHFRVAL IPFFAAFCLP VFAHPETLVK VKDAEDQLGA RVGYIELDLN SGKILESFRP EERFPMMSTF KVLLCGAVLS RVDAGQEQLG RRIHYSQNDL VEYSPVTEKH LTDGMTVREL CSAAITMSDN TAANLLLTTI GGPKELTAFL HNMGDHVTRL DRWEPELNEA IPNDERDTTM PAAMATTLRK LLTGELLTLA SRQQLIDWME ADKVAGPLLR SALPAGWFIA DKSGAGERGS RGIIAALGPD GKPSRIVVIY TTGSQATMDE RNRQIAEIGA SLIKHW.

The beta lactam antibiotics (penicillins and cephalosporins) are the most frequently used antimicrobial agents. All of the beta lactams are structurally related through the presence of a core beta lactam ring. Bacterial resistance to beta lactams continues to increase, primarily due to the production of beta lactamases. Beta lactamases catalyze the hydrolysis of the beta lactam bond, which destroys antibacterial activity. Bacteria that produce TEM type or SHV type beta lactamases have point mutations in structural genes that have extended the substrate specificity of these beta lactamases. As a result, many of the beta lactamase producing Gram negative pathogens have become multidrug resistant.

Specifications

• Antigen: beta Lactamase
• Classification: Monoclonal
• Concentration: 1.8 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Target Species: Bacteria
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot
• Clone: 8A5.A10
• Conjugate: Unconjugated
• Gene Alias: blaCTX-M-14; FLJ14902; G24; lactamase beta; LACTB; mitochondrial 39S ribosomal protein L56; MRPL56; Serine beta-lactamase-like protein LACTB, mitochondrial; UNQ843/PRO1781
• Immunogen: 5'-His-tagged E. coli 205 TEM-1 R+ beta-lactamase.
• Quantity: 500 μg
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid