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  6. Invitrogen™ beta Synuclein Monoclonal Antibody (6A10)

Invitrogen™ beta Synuclein Monoclonal Antibody (6A10)

Catalog No. PIMA547356
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500 μL
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PIMA547356 500 μL
PIMA547455 100 μL
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Catalog No. PIMA547356 Supplier Invitrogen™ Supplier No. MA547356
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Description

Mouse Monoclonal Antibody

beta Synuclein Monoclonal Antibody for Western Blot, ICC/IF, IHC (PFA)

Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's PD) and breast cancer. In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of alpha synuclein has been linked to many familial cases of PD. In breast cancer increased expression of gamma synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.
TRUSTED_SUSTAINABILITY

Specifications

Antigen beta Synuclein
Applications Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 6A10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 5mM sodium azide
Gene SNCB
Gene Accession No. P33567, Q16143, Q63754, Q91ZZ3
Gene Alias AI838531; betaSYN; beta-synuclein; Phosphoneuroprotein 14; PNP 14; Sncb; synuclein beta; synuclein, beta
Gene Symbols SNCB
Host Species Mouse
Immunogen C-terminal peptide of human beta-synuclein EPEGESYEDPPQEEYQEYEPEA coupled to KLH.
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100127169, 104069, 113893, 508421, 6620
Target Species Human, Mouse, Rat, Bovine, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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