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Invitrogen™ beta Synuclein Polyclonal Antibody

Catalog No. PIPA5143523
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500 μL
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PIPA5143523 500 μL
PIPA5143621 100 μL
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Catalog No. PIPA5143523 Supplier Invitrogen™ Supplier No. PA5143523
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Rabbit Polyclonal Antibody

beta Synuclein Polyclonal Antibody for Western Blot, ICC/IF, IHC (PFA)

Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's PD) and breast cancer. In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of alpha synuclein has been linked to many familial cases of PD. In breast cancer increased expression of gamma synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.
TRUSTED_SUSTAINABILITY

Specifications

Antigen beta Synuclein
Applications Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 5mM sodium azide
Gene SNCB
Gene Accession No. P33567, Q16143, Q63754, Q91ZZ3
Gene Alias AI838531; betaSYN; beta-synuclein; Phosphoneuroprotein 14; PNP 14; Sncb; synuclein beta; synuclein, beta
Gene Symbols SNCB
Host Species Rabbit
Immunogen Full length human recombinant beta-Synuclein protein expressed in and purified from E. Coli.
Purification Method Affinity chromatography
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100127169, 104069, 113893, 508421, 6620
Target Species Human, Mouse, Rat, Bovine, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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