beta TrCP2Rabbit anti-Bovine, Canine, Chicken, Human, Monkey, Mouse, Polyclonal, Rockland™

Rabbit Polyclonal Antibody

Supplier:  Rockland Immunochemicals 600401483

Catalog No. 50-199-1773

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This antibody reacts with human betaTrCP2 protein. A BLAST analysis was used to suggest cross-reactivity with betaTrCP2 from human, mouse, dog, bovine, chimpanzee, chicken and horse based on a 100% homology with the immunizing sequence. Cross-reactivity with betaTrCP2 from other sources has not been determined.

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.

Specifications

• Antigen: beta TrCP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fbxw11
• Gene Alias: 2310065A07Rik; AA536858; beta-transducin repeat-containing protein 2; BTRC2; BTRCP2; F-box and WD repeat domain containing 11; F-box and WD repeats protein beta-TrCP2; F-box and WD-40 domain protein 11; F-box and WD-40 domain protein 1B; F-box protein Fbw1b; F-box/WD repeat-containing protein 11; F-box/WD repeat-containing protein 1B; Fbw11; Fbw1b; FBXW11; Fbxw1b; Homologous to Slimb protein; HOS; KIAA0696
• Host Species: Rabbit
• Regulatory Status: RUO
• Gene ID (Entrez): 103583, 23291, 416181, 479291, 540642
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
• Concentration: 0.8 mg/mL
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Accession No.: Q5SRY7, Q9UKB1
• Gene Symbols: Fbxw11
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Bovine, Canine, Chicken, Human, Monkey, Mouse
• Product Type: Antibody