Invitrogen™ betatrophin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA538043

Catalog No. PIPA538043

Description

A recommended positive control is rat liver tissue lysate. At least three isoforms of Betatrophin are known to exist; this antibody will detect the two largest isoforms.

The Betatrophin protein, also known as the hepatocellular carcinoma-associated protein TD26, is an adipocyte- and liver-enriched insulin targeted gene that is thought to play a role in lipid metabolism be regulating serum triglyceride levels. Betatrophin is closely related to the angiopoietin-like (ANGPTL) protein family. Betatrophin mRNA increases in the cold environment and after treatment with a high-fat diet, while its mRNA levels decrease in response to fasting, suggesting that it may play a role in mediating thermogenesis and energy homeostasis.

Specifications

• Antigen: betatrophin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ANGPTL8
• Gene Alias: angiopoietin like 8; angiopoietin-like 8; angiopoietin-like protein 8; Angptl8; betatrophin; betatrophin variant 1; betatrophin variant 2; C19orf80; EG624219; Gm6484; hepatocellular carcinoma-associated gene TD26; hepatocellular carcinoma-associated protein TD26; hepatocellular carcinoma-associated protein TD26 homolog; lipasin; LOC100361444; predicted gene 6484; PRO1185; PVPA599; rCG31799-like; refeeding-induced fat and liver protein; Rifl; TD26; UNQ599/PRO1185
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100361444, 55908, 624219
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q6UXH0, Q8R1L8
• Gene Symbols: ANGPTL8
• Immunogen: 16 amino acid peptide near the amino terminus of human Betatrophin.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov