Invitrogen™ BEX1/BEX2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100404

Catalog No. PIPA5100404

Description

Antibody detects endogenous levels of total BEX1/2.

BEX1/BEX2 belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. BEX1/BEX2 has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: BEX1/BEX2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BEX1
• Gene Alias: AA407839; AL024066; AU018692; BEX1; BEX2; Bex4; brain expressed gene 1; brain expressed X-linked 1; brain expressed X-linked 2; brain expressed, X-linked 1; brain-expressed X-linked protein 1; Brain-expressed X-linked protein 1 homolog; brain-expressed X-linked protein 2; Brain-expressed X-linked protein 2 homolog; DJ79P11.1; EG2RVC; expression gene 2 in rat visual cortex; hBex2; HGR74-h; ovarian granulosa cell 13.0 kDa protein hGR74; protein BEX1; Protein BEX2; protein hBex2; reduced expression 3; reduced expression protein 3; Rex3; REX-3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12069, 19716, 363498, 501625, 55859, 84707
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q3MKQ1, Q3MKQ2, Q9BXY8, Q9HBH7, Q9R224, Q9WTZ8
• Gene Symbols: BEX1, BEX2
• Immunogen: A synthesized peptide derived from human BEX2(Accession Q9BXY8), corresponding to amino acid residues M1-R50.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov