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  5. Tocris Bioscience™ BGP 15

Tocris Bioscience™ BGP 15
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Catalog No. 67035
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25 mg
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Catalog No. Quantity
67-035 5 mg
67-032-5 25 mg
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Catalog No. 67-035 Supplier Tocris Bioscience™ Supplier No. 6703/5
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Description

PARP inhibitor; cytoprotectant

BGP 15 is a PARP inhibitor (IC50 = 120 μM). Displays cytoprotective effects in various disease models: decreases ROS levels, lipid peroxidation and single-strand DNA breaks in isolated reperfused rat hearts; improves mitochondrial function and protects against neuronal cell death in a mouse model of familial dysautonomia. Also activates HSP70 in rodent skeletal muscle, increasing oxidative capacity and improving insulin sensitivity.

Specifications

Quantity 5 mg
Molecular Formula C14H22N4O2.2HCl
Formula Weight 351.27
Product Type Inhibitor
Purity 98%
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