Invitrogen™ BHLHB5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA564189

Catalog No. PIPA564189

Description

Immunogen sequence: EDDLFLHKSL SASTSKRLEA AFRSTPPGMD LSLAPPPRER PASSSSSPLG CFEPADPEGA GLLLPPP Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 93%.

BHLHB5 inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. BHLHB5 despite the presence of an intact basic domain, does not bind to DNA.

Specifications

• Antigen: BHLHB5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BHLHE22
• Gene Alias: basic helix-loop-helix (bHLH) gene, class B, beta3; basic helix-loop-helix domain containing, class B, 5; basic helix-loop-helix domain containing, class B5; basic helix-loop-helix family member e22; basic helix-loop-helix family, member e22; Beta3; BHLHB5; bHLHe22; CAGL85; Class B basic helix-loop-helix protein 5; class E basic helix-loop-helix protein 22; Protein BETA3; TNRC20; trinucleotide repeat containing 20; trinucleotide repeat-containing gene 20 protein
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27319
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.16 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8NFJ8
• Gene Symbols: BHLHE22
• Immunogen: Recombinant protein corresponding to Human BHLHB5. Recombinant protein control fragment (Product #RP-103577).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG