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R&D Systems™ BI 78D3
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Catalog No. 331450 Shop All Novus Products
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Catalog No. Quantity
33-145-0 50 mg
33-141-0 10 mg
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Catalog No. 33-145-0 Supplier R&D Systems™ Supplier No. 3314/50

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Description

A Tocris product, part of R&D Systems. Selective, competitive JNK inhibitor

Competitive c-Jun N-terminal kinase (JNK) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. Inhibits JNK interacting protein 1 (JIP1)-JNK binding (IC50 = 500 nM) and prevents JNK substrate phosphorylation. Blocks JNK-dependent Con A-induced liver damage and restores insulin sensitivity in a mouse model of type II diabetes.

Chemical Identifiers

CAS 883065-90-5
Molecular Formula C13H9N5O5S2

Specifications

Quantity 50 mg
Product Line Tocris
Formula Weight 379.37
Purity >99%
Molecular Weight (g/mol) 379.365
Chemical Name or Material BI 78D3

Safety and Handling

Recommended Storage Store at +4°C
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