Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ BI 78D3

Tocris Bioscience™ BI 78D3
GREENER_CHOICE

Catalog No. 331410
Change view
Click to view available options
Quantity:
10 mg
50 mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
33-141-0 10 mg
33-145-0 50 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Catalog No. 33-141-0 Supplier Tocris Bioscience™ Supplier No. 3314/10
Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

Selective, competitive JNK inhibitor

Competitive c-Jun N-terminal kinase (JNK) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. Inhibits JNK interacting protein 1 (JIP1)-JNK binding (IC50 = 500 nM) and prevents JNK substrate phosphorylation. Blocks JNK-dependent Con A-induced liver damage and restores insulin sensitivity in a mouse model of type II diabetes.

Chemical Identifiers

CAS 883065-90-5
Molecular Formula C13H9N5O5S2

Specifications

Quantity 10 mg
Formula Weight 379.37
Purity >99%
Molecular Weight (g/mol) 379.365
Chemical Name or Material BI 78D3

Safety and Handling

Recommended Storage Store at +4°C
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.