Invitrogen™ Biglycan Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596232

Catalog No. PIPA596232

Description

Immunogen sequence: EQRGFWDFTL DDGPFMMNDE EASGADTSGV LDPDSVTPTY SAMCPFGCHC HLRVVQCSDL GLKSVPKEIS PDTTLLDLQN NDISELRKDD FKGLQHLYAL VLVNNKISKI HEKAFSPLRK LQKLYISKNH LVEIPPNLPS SLVELRIHDN RIRKVPKGVF SGLRNMNCIE MGGNPLENSG FEPGAFDGLK LNYLRISEAK LTGIPKDLPE T; Positive Samples: U-87MG, HepG2; Cellular Location: extracellular matrix, extracellular space.

BGN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein is thought to function in connective tissue metabolism by binding to collagen fibrils and transferring growth factor-beta. It may promote neuronal survival.

Specifications

• Antigen: Biglycan
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BGN
• Gene Alias: BG; BGN; Biglycan; bone/cartilage proteclycan 1; bone/cartilage proteoglycan I; bone/cartilage proteoglycan-I; BSPG1; dermatan sulphate proteoglycan I; DSPG1; PG S1; PGI; PG-S1; SLRR1A; small leucine-rich protein 1A; Small proteoglycan I (biglycan), bone (BSPG1) (bone/cartilage proteclycan 1 precursor)
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 633
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 4.81 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P21810
• Gene Symbols: BGN
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-230 of human BGN (NP_0017021).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov