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Invitrogen™ BIKE Polyclonal Antibody
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Catalog No. PIPA533369
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50 μg
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Catalog No. Quantity
PIPA533369 50 μg
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Catalog No. PIPA533369 Supplier Invitrogen™ Supplier No. PA533369
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Mouse (93%); Chicken, Zebrafish (87%). Antigen retrieval requires Proteinase K treatment.

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. BMP2K (BMP2 inducible kinase), also known as BIKE, is a 1,161 amino acid nuclear protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Thought to be involved in osteoblast differentiation, BMP2K catalyzes the ATP-dependent phosphorylation of bone morphogenic proteins (BMPs); proteins that are essential for proper cartilage and bone formation. Via its catalytic activity, BMP2K may play a role in signaling pathways that mediate bone growth and cellular differentiation. Three isoforms of BMP2K exist due to alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BIKE
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene BMP2K
Gene Accession No. Q9NSY1
Gene Alias 4933417M22Rik; AA673486; AV128808; BIKE; Bike kinase; BMP2 inducible kinase; BMP-2 inducible kinase; BMP-2-inducible protein kinase; Bmp2k; HRIHFB2017
Gene Symbols BMP2K
Host Species Rabbit
Immunogen Synthetic 15 amino acid peptide from N-terminus of human BMP2K.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55589
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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