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Invitrogen™ ACVR2B (Bimagrumab Biosimilar) Recombinant Human Monoclonal Antibody
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Catalog No. PIMA541992
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100 μg
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PIMA541992 100 μg
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Catalog No. PIMA541992 Supplier Invitrogen™ Supplier No. MA541992
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Description

Human Recombinant Monoclonal Antibody

Endotoxin level <0.01EU/μg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.

ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACVR2B (Bimagrumab Biosimilar)
Applications ELISA, Flow Cytometry
Classification Recombinant Monoclonal
Concentration 1.99 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene ACVR2B
Gene Accession No. Q13705
Gene Alias activin A receptor type 2B; activin A receptor type IIB; activin A receptor, type IIB; activin receptor IIB; activin receptor type IIB; Activin receptor type-2B; Activine receptor 2b (transmembrane serine kinase); ActRIIB; ACTR-IIB; ActRIIB type II activin receptor B; ACVR2B; HTX4; MGC116908
Gene Symbols ACVR2B
Host Species Human
Immunogen Human ACVR2A/ACVR2B.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 93
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1 λ
Target Molecule Chemical
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