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Bin1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories, Inc A302728AT

Description
The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dyim, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.Specifications
Bin1 | |
Polyclonal | |
Unconjugated | |
BIN1 | |
BIN1; bridging integrator 1; AMPH2; AMPHL; DKFZp547F068; MGC10367; SH3P9; amphiphysin II; amphiphysin-like; box dependant MYC interacting protein 1 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
274 | |
4° C | |
Liquid |
Immunohistochemistry, Immunoprecipitation | |
1 mg/ml | |
phosphate, tris citrate with 0.09% sodium azide; pH 7-8 | |
O00499 | |
BIN1 | |
Between 300 and 350 | |
10 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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