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Bin1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501563323
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50-156-3323 10 μL
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Catalog No. 50-156-3323 Supplier Bethyl Laboratories, Inc Supplier No. A302728AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat

This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dyim, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

Specifications

Antigen Bin1
Applications Immunohistochemistry, Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene BIN1
Gene Accession No. O00499
Gene Alias BIN1; bridging integrator 1; AMPH2; AMPHL; DKFZp547F068; MGC10367; SH3P9; amphiphysin II; amphiphysin-like; box dependant MYC interacting protein 1
Gene Symbols BIN1
Host Species Rabbit
Immunogen Between 300 and 350
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 274
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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