Invitrogen™ BIN2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558486

Catalog No. PIPA558486

Description

Immunogen sequence: EKPVRTPEAK ENENIHNQNP EELCTSPTLM TSQVASEPGE AKKMEDKEKD NKLISADSSE GQDQLQVSMV PENNNLTAPE PQEEVSTSEN PQL Highest antigen sequence identity to the following orthologs: Mouse - 29%, Rat - 31%.

BAR proteins, which are characterized by a common N-terminal BAR domain, are a family of adaptor proteins implicated in a diverse set of cellular processes. BIN1 (bridging integrator 1) and BIN2 are BAR proteins. The human BIN2 gene is located at chromosome 4q22.1, and encodes a 565-amino acid protein with a predicted molecular weight of ~62 kDa. It shows preferential expression in hematopoietic tissues, with highest mRNA levels in spleen and peripheral blood leukocytes and also high levels in thymus, colon, and placenta. BIN2 has been shown to migrate with an apparent mobility of ~80 kDa, and interact with BIN1.

Specifications

• Antigen: BIN2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BIN2
• Gene Alias: BIN2; BRAP1; BRAP-1; breast cancer associated protein BRAP1; breast cancer-associated protein 1; Bridging integrator 2; bridging integrator-2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51411
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UBW5
• Gene Symbols: BIN2
• Immunogen: Recombinant protein corresponding to Human BIN2. Recombinant protein control fragment (Product #RP-97670).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG