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Corning™ BioCoat™ 384-Well, Poly-D Lysine-Treated, Flat-Bottom Microplate

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20/Pk., 80/Cs.

Color: Black, Clear Bottom; Sterility: Non-sterile; Lid: With Lid

Poly-D-Lysine (PDL) and Poly-L-Lysine (PLL) are synthetic compounds that enhance cell adhesion and protein absorption by altering surface charges on the culture substrate. In addition to promoting cell adhesion, poly-lysine surface treatments support neurite outgrowth and improve the survival of many central nervous system (CNS) primary cells in culture. As PDL and PLL are synthetic molecules, they do not stimulate biological activity in the cells cultured on them, and they do not introduce impurities carried by natural polymers.

Applications include:

  • Attachment and spreading of a variety of cell types
  • Cell differentiation and neurite outgrowth
  • Attachment of fastidious transfected cell lines
  • Support survival of primary neurons in culture
  • Serum-free or reduced-serum culture


  • PDL, synthetic (MW 75-150 kD)
  • PLL, synthetic (MW 30-70 kD)

Quality Control

  • Tested for ability to promote firm attachment of RCG cells
  • Tested and found negative for bacteria and fungi


  • 4°C to 30°C under dry conditions.
  • Bottom Flat
    Certifications/Compliance ANSI, SBS
    Color Black, Clear Bottom
    For Use With (Application) Attachment and spreading of a variety of cell types, cell differentiation and neurite outgrowth, attachment of fastidious transfected cell lines, support survival of primary neurons in culture, serum-free or reduced serum culture
    Material Polystyrene
    Quantity 5/Case
    Source Poly-D-Lysine
    Storage Requirements 4°C to 30°C
    Sterility Non-sterile
    Well Color Clear
    Surface Treatment Cell Culture
    No. of Wells 384
    Array 16 x 24
    Lid With Lid
    Packaging 5/Case
    Type Standard
    Format Standard
    Well Shape Round
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