Tocris Bioscience BIRB 796
High affinity and selective p38 kinase inhibitor
Manufacturer: Tocris Bioscience 5989/50
DescriptionHigh affinity and selective p38 kinase inhibitor (Kd = 50-100 pM). Exhibits no significant inhibition on a panel of related kinases. Inhibits LPS-induced TNFα production in human PBMCs and whole blood (IC50 values are 21 and 960 nM, respectively). Also inhibits JNK2α2 and c-Raf-1 (IC50 values are 98 nM and 1.4 μM, respectively). Cell permeable.
|Target: p38 Inhibitors|
Safety and Handling
Recommended Storage : Store at −20°C
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