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Tocris Bioscience™ BIRB 796

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Quantity:
10 mg
50 mg
Description
BIRB 796 is a high affinity and selective p38 kinase inhibitor (Kd = 50-100 pM). Exhibits no significant inhibition on a panel of related kinases. Inhibits LPS-induced TNFα production in human PBMCs and whole blood (IC50 values are 21 and 960 nM, respectively). Also inhibits JNK2α2 and c-Raf-1 (IC50 values are 98 nM and 1.4 μM, respectively). Cell permeable.
Specifications
Specifications
Chemical Name or Material | N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N′-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea |
CAS | 285983-48-4 |
Synonym | Doramapimod |
Quantity | 50 mg |
Target | p38 Inhibitors |
Molecular Formula | C31H37N5O3 |
Formula Weight | 527.66 |
Purity | 0.98 |
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