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BIRC7 Mouse anti-Human, Clone: OTI1B10, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA500761

Catalog No. 50-167-1903


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Description

Description

The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity. Recently, it has been identified that a novel human inhibitor of apoptosis protein (IAP) family member termed Livin or ML-IAP, which contains a single baculoviral IAP repeat (BIR) domain and a COOH-terminal RING finger domain. Livin gene has two splicing variants that contain open reading frames of 298 and 280 amino acids and both contained a single copy of baculovirus IAP repeat (BIR) and RING domain. Both of the isoforms inhibit TNFa induced apoptosis in Jurkat cells. Livin expression is low in adult tissues. It is relatively expressed at a higher level in developmental tissues and in many cancer cells.
Specifications

Specifications

BIRC7
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q96CA5
KIAP, LIVIN, ML-IAP, MLIAP, RNF50
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
79444
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI1B10
Unconjugated
BIRC7
Liquid
BIRC7
Full length human recombit protein of human BIRC7 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
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