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Tocris Bioscience™ BIX 02189
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Catalog No. 484210
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Catalog No. Quantity
48-421-0 10 mg
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Description

Selective MEK5 and ERK5 inhibitor

BIX 02189 is a selective MEK5 and ERK5 inhibitor (IC50 values are 1.5 and 59 nM respectively). Inhibits sorbitol-induced ERK5 phosphorylation in HeLa cells. Selective for MEK5 and ERK5 over MEK1/2, ERK1/2 and a panel of 87 kinases. Induces apoptosis in acute myeloid leukemia tumor cells.

Specifications

Quantity 10 mg
Product Type BIX 02189
Purity >98%
Molecular Weight (g/mol) 440.54
Inhibitors BIX 02189

For Research Use Only

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