Invitrogen™ BLK Monoclonal Antibody (1E6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515725

Catalog No. PIMA515725

Description

MA5-15725 targets BLK in indirect ELISA, FACS, IF, and WB applications and shows reactivity with Human samples. The MA5-15725 immunogen is purified recombinant fragment of human BLK expressed in E. Coli. MA5-15725 detects BLK which has a predicted molecular weight of approximately 58kDa.

B-lymphoid tyrosine kinase (BLK) is a non-receptor tyrosine kinase that belongs to the Src family of kinases. BLK plays an important role in B-cell activation. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.

Specifications

• Antigen: BLK
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: P51451
• Gene Symbols: BLK
• Immunogen: Purified recombinant fragment of human BLK expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 640
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 1E6
• Conjugate: Unconjugated
• Gene: BLK
• Gene Alias: B lymphocyte kinase; B lymphoid kinase; B lymphoid tyrosine kinase; Blk; BLK nonreceptor tyrosine kinase; BLK proto-oncogene, Src family tyrosine kinase; MGC10442; MODY11; p55-Blk; tyrosine-protein kinase Blk
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1